A synthetic cardiac tetrapeptide (AEDR) from the Khavinson line, mapped mainly through organotypic mesoderm proliferation work.
AEDR
Ala · Glu · Asp · Arg
Cardiogen is the synthetic tetrapeptide Ala-Glu-Asp-Arg from the Khavinson cardiac line. Same school shelf as epitalon, different terminal residue and tissue frame.
It is distinct from the porcine cardiac fraction cardialin. Synthetic defined sequence versus mixed extract.
We keep it because AEDR appears in the school's short-peptide family lists and in at least one clear organotypic proliferation paper.
Themed chapters drawn only from papers already mapped on this dossier. Archive map. No medical advice.
Ivanova, Zalomaeva, Chalikova and co-authors (2022) report tissue-specific oligopeptides, including the cardiogen-class AEDR frame, stimulating cellular proliferation primarily in myocardium, vessels and muscles. The paper pairs that readout with weak static magnetic field comparisons.
A 2006 PubMed organotypic title on tissue-specific synthetic peptide regulators in young and old rats sits in the same experimental neighbourhood.
School reviews on medicinal peptide preparations and peptide bioregulators in elderly care place cardiogen among the synthetic tetrapeptide set. Those reviews are family context, not a dedicated cardiogen monograph.
The usable trail is Chalikova-lab organotypic culture plus school family reviews. Infarct, COVID myocarditis and BNP titles that share search tokens are treated as retrieval noise.
One PubMed COVID mortality-index hit in the prior map is off-topic for the peptide and is dropped.
3 in corpus · off-topic retrieval rows removed (STEMI prognosis, AV-block pacing, elderly MI care, deltorphin opioid, glycaemia in MI, stenting, COVID myocarditis, acute HF algorithms)
1 curated · off-topic COVID VACO index row removed
Reviewed against the archive corpora on 2026-09-19. Source-grounded. No clinical claims. Archive / history / research only. No medical advice. No dosing, synthesis, sourcing, or health claims.